CCND2 CLIA Kit for Pig(Sus scrofa) | EIAab.comCCND2 CLIA Kit for Pig(Sus scrofa)

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Index > Protein center > CCND2(Gene name) > Pig

CCND2 (Gene name),

G1/S-specific cyclin-D2 (Protein name ), CCND2_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CCND2;

Protein name:

G1/S-specific cyclin-D2;

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Interacts with either CDK4 or CDK6 protein kinase to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Component of the ternary complex cyclin D/CDK4/CDKN1B required for nuclear translocation and modulation of CDK4-mediated kinase activity.

Function:

Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Subcellular Location:

Nucleus Cytoplasm Membrane Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members.

Protein Attributes:

Sequence length:

288

Sequence:

50:

100:

150:

200:

250:

288:

EVVLLNSLQQ | YRQDQDGSKS | EDELDQASTP | TDVRDIDL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF02984

STRING:

9823.ENSSSCP00000000774

KEGG:

ssc:397162

UniGene:

Ssc.79862

String:

Q8WNW2

UniGene:

Ssc.15749

Uniprot:

Q8WNW2

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ELISA Kit for Pig G1/S-specific cyclin-D2

Cat.:

E0586h

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96T

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ELISA Kit for Pig G1/S-specific cyclin-D2

Cat.:

E0586m

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96T

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ELISA Kit for Pig G1/S-specific cyclin-D2

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E0586p

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96T

ELISA Kit for Pig G1/S-specific cyclin-D2

Cat.:

E0586b

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96T

ELISA Kit for Pig G1/S-specific cyclin-D2

Cat.:

E0586c

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ELISA Kit for Pig G1/S-specific cyclin-D2

Cat.:

E0586r

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96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586c

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Packing:

96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586b

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Packing:

96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586r

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MSDS:

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Packing:

96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586h

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig G1/S-specific cyclin-D2

Cat.:

U0586p

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96T

Polyclonal Antibody for Pig G1/S-specific cyclin-D2

Cat.:

P0586Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig G1/S-specific cyclin-D2

Cat.:

P0586Rb-m

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40ug/0.2ml

Polyclonal Antibody for Pig G1/S-specific cyclin-D2

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P0586Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Pig G1/S-specific cyclin-D2

Protein for Pig G1/S-specific cyclin-D2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Transcriptional upregulation of p27Kip1 during contact-induced growth arrest in endotehlial cells."
Hirano M. , Hirano K. , Nishimura J. , Kanaide H.
Submitted (2000-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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